I have used Eco One for over 2 years with no problems. We use our spa daily and never have any skin problems or water problems. My spa is 450 gals and we add a bottle of Eco One every month. We also add 2 tablespoons of NON-CHLORINE shock every week. I only change my water every 6 months or so. This product is GREAT!!!. I highly recommend this product to everyone!!!!